What has been found to be the median time to best response with enasidenib?

Published on May 23, 2018 in Treatment

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Hetty E. Carraway, MD
Staff Physician
Hematologic Oncology and Blood Disorders
Taussig Cancer Institute, Cleveland Clinic
Cleveland, Ohio

Welcome to Managing AML, I am Dr. Hetty Carraway. Today, I would like to discuss what has been found to be the median time to best response with enasidenib. In this setting, we know that patients have a median time to response of about 1.9 or 2 months with enasidenib. For that reason, we would like to encourage clinicians to keep patients on therapy for some duration of time. Here, the question is really what is the median time to best response, and for many of these patients that can be at least four to five months on therapy, and for some patients, out to seven to eight months on therapy. For that reason, it is important to remember for those patients that are being treated with enasidenib 100 mg once a day, before stopping therapy, it is prudent to keep them on therapy for at least four to five months to determine how they are doing. The median time to best response may be beyond that, out to seven or eight months. Thank you for viewing this activity.

Last modified: May 14, 2018

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