Managing High-Risk and Relapsed/Refractory AML: Where Is Research Headed Next?
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Release Date: November 28, 2018
Expiration Date: November 28, 2019
Expected time to complete this activity as designed: 30 minutes
There are no fees for participating in or receiving credit for this online activity.
With the treatment landscape for acute myeloid leukemia (AML) continuing to expand, it is critical for physicians to be up-to-date on the emerging role of FDA-approved therapies and combinations as well as those being explored in clinical trials. In this activity, Dr. Amir Fathi describes the emerging role of FLT3 and IDH1/2 inhibitors in AML. He also discusses the treatment paradigm for non-intensive, upfront therapy when caring for older or less functionally robust patients with the disease.
This activity is designed for multidisciplinary healthcare providers in the community setting, including hematologists, oncologists, pharmacists and other allied healthcare professionals who provide care to patients with acute myeloid leukemia.
Upon completion of this educational activity, participants should be able to:
- Describe the emerging role of FLT3 and IDH1/2 inhibitors in AML
- Discuss the paradigm for non-intensive, upfront treatment of older or less functionally robust patients with AML
Managing High-Risk and Relapsed/Refractory AML: Where Is Research Headed Next? - Amir T. Fathi, MD
Instructions for Participation and Credit
This activity is eligible for credit through November 28, 2019. After this date, this activity will expire and no further credit will be awarded.
- Read the target audience, learning objectives, and faculty disclosures.
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- Complete the educational content as designed.
- Complete the post-test. To receive a certificate, you must receive a passing score of 70%.
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- Certificates for CME may be printed immediately after successfully completing the post-test and activity evaluation. Pharmacist credit will be uploaded to CPE Monitor 4 weeks following receipt of a completed, qualified form.
Amir T. Fathi, MD
Program Director, Center for Leukemia
Massachusetts General Hospital Cancer Center
Assistant Professor in Medicine
Harvard Medical School
Dr. Amir Fathi graduated summa cum laude from Yale University with a BS degree in molecular, cellular, and developmental biology. He went on to receive his medical degree with honors at the Yale School of Medicine. He also has a master’s degree in epidemiology from Harvard School of Public Health. Dr. Fathi completed his residency training in internal medicine at Massachusetts General Hospital (MGH), and fellowships in both hematology and medical oncology at Johns Hopkins Hospital. He is the Program Director of the Center for Leukemia at the Massachusetts General Hospital Cancer Center; he is also an Assistant Professor in Medicine at Harvard Medical School.
Dr. Fathi has presented at national meetings of the American Society of Clinical Oncology (ASCO) and the American Society of Hematology (ASH), spoken at national academic and educational meetings, and has served on national committees that establish guidelines for the management of acute and chronic leukemias. As faculty at the MGH Cancer Center and Harvard Medical School, Dr. Fathi provides clinical care, supervises trainees, administers a busy clinic, and as the director of clinical research in leukemia, is the lead investigator on numerous clinical trials investigating novel treatments in acute leukemias.
Outcomes for patients with acute myeloid leukemia (AML) continue to be poor despite incremental advances in treatment and supportive care over the last 30 years. Although most patients respond to initial treatment, the majority eventually relapse and many succumb to their disease. Therefore, new and innovative approaches are desperately needed to significantly improve outcomes. As a clinician-scientist with a deep interest in developing novel therapies for AML, Dr. Fathi endeavors to provide outstanding clinical care, teaching, and mentoring, while also conducting translational projects, retrospective research, and clinical trials, with the overarching goal improving the health and outcomes of patients with bone marrow malignancies.
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Provided by MediCom Worldwide, Inc.
This activity is supported by educational grants from Agios Pharmaceuticals, Inc., Celgene Corporation, Daiichi Sankyo, Inc., Helsinn Healthcare SA, and Jazz Pharmaceuticals
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Accreditation Statement: MediCom Worldwide, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation Statement: MediCom Worldwide, Inc. designates this enduring material for a maximum of 0.50 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
MediCom Worldwide, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity is acceptable for 0.50 contact hours of Continuing Education Credit. Universal Activity Number: 827-0000-18-042-H01-P. Knowledge-based CPE activity.
In order for CPE Monitor to authenticate credit, pharmacists/technicians must provide their e-Profile ID number from NABP and date of birth (in MMDD format) when claiming credit for a CPE program.
As an organization accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE) and California State Board of Registered Nursing, MediCom Worldwide, Inc. requires everyone who is in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest. Accordingly, the following disclosures were made.
Dr. Amir Fathi has received honoraria related to formal advisory activities from Agios, Astellas Pharma US, Inc., and Jazz Pharmaceuticals plc, as well as consultant fees from Celgene Corporation, Clear Creek Bio, Inc., Novartis AG, and Takeda Oncology.
Planning Committee Disclosures
The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Kristin Burke, Project Manager, Keith D’Oria, Medical Writer, and Joan Meyer, RN, MHA, Executive Director, have no relevant financial relationships.
Peer Reviewer Disclosure
In accordance with MediCom Worldwide, Inc. policy, all content is reviewed by external independent peer reviewers for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.